EMBO Mol Med. 2016 Aug 1;8(8):967-86. doi: 10.15252/emmm.201505944.
Capuani C, Melone M, Tottene A, Bragina L, Crivellaro G, Santello M, Casari G, Conti F, Pietrobon D.
Category Archives: Chromatin News
Chromatin and Epigenetics News
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer.
Nat Cell Biol. 2016 Aug;18(8):897-909. doi: 10.1038/ncb3380. Epub 2016 Jun 27.
Walerych D, Lisek K, Sommaggio R, Piazza S, Ciani Y, Dalla E, Rajkowska K, Gaweda-Walerych K, Ingallina E, Tonelli C, Morelli MJ, Amato A, Eterno V, Zambelli A, Rosato A, Amati B, Wiśniewski JR, Del Sal G.
PML nuclear body disruption impairs DNA double-strand break sensing and repair in APL.
Cell Death Dis. 2016 Jul 28;7:e2308. doi: 10.1038/cddis.2016.115.
di Masi A, Cilli D, Berardinelli F, Talarico A, Pallavicini I, Pennisi R, Leone S, Antoccia A, Noguera NI, Lo-Coco F, Ascenzi P, Minucci S, Nervi C.
Compensatory RNA polymerase 2 loading determines the efficacy and transcriptional selectivity of JQ1 in Myc-driven tumors.
Leukemia. 2016 Jul 22. doi: 10.1038/leu.2016.182. [Epub ahead of print]
Donato E, Croci O, Sabò A, Muller H, Morelli MJ, Pelizzola M, Campaner S.
Minor intron splicing is regulated by FUS and affected by ALS-associated FUS mutants.
EMBO J. 2016 Jul 15;35(14):1504-21. doi: 10.15252/embj.201593791. Epub 2016 Jun 1.
Reber S, Stettler J, Filosa G, Colombo M, Jutzi D, Lenzken SC, Schweingruber C, Bruggmann R, Bachi A, Barabino SM, Mühlemann O, Ruepp MD.
Uncontrolled IL-17 Production by Intraepithelial Lymphocytes in a Case of non-IPEX Autoimmune Enteropathy.
Clin Transl Gastroenterol. 2016 Jul 14;7(7):e182. doi: 10.1038/ctg.2016.41.
Paroni M, Magarotto A, Tartari S, Nizzoli G, Larghi P, Ercoli G, Gianelli U, Pagani M, Elli L, Abrignani S, Conte D, Geginat J, Caprioli F.
Identity by descent fine mapping of familial adult myoclonus epilepsy (FAME) to 2p11.2-2q11.2.
Hum Genet. 2016 Jul 1. [Epub ahead of print]
Henden L, Freytag S, Afawi Z, Baldassari S, Berkovic SF, Bisulli F, Canafoglia L, Casari G, Crompton DE, Depienne C, Gecz J, Guerrini R, Helbig I, Hirsch E, Keren B, Klein KM, Labauge P, LeGuern E, Licchetta L, Mei D, Nava C, Pippucci T, Rudolf G, Scheffer IE, Striano P, Tinuper P, Zara F, Corbett M, Bahlo M.
HMGB1 as biomarker and drug target.
Pharmacol Res. 2016 Jul 1;111:534-544. doi: 10.1016/j.phrs.2016.06.031. [Epub ahead of print]
Venereau E, De Leo F, Mezzapelle R, Careccia G, Musco G, Bianchi ME.
Quantitative assessment of chemical artefacts produced by propionylation of histones prior to mass spectrometry analysis.
Proteomics. 2016 Jul;16(14):1952-4. doi: 10.1002/pmic.201600173.
Soldi M, Cuomo A, Bonaldi T.
Specificity and Function of IRF Family Transcription Factors: Insights from Genomics.
J Interferon Cytokine Res. 2016 Jul;36(7):462-9. doi: 10.1089/jir.2016.0004.
Mancino A, Natoli G.
Transcription factor TLX1 controls retinoic acid signaling to ensure spleen development.
J Clin Invest. 2016 Jul 1;126(7):2452-64. doi: 10.1172/JCI82956. Epub 2016 May 23.
Lenti E, Farinello D, Yokoyama KK, Penkov D, Castagnaro L, Lavorgna G, Wuputra K, Sandell LL, Tjaden NE, Bernassola F, Caridi N, De Antoni A, Wagner M, Kozinc K, Niederreither K, Blasi F, Pasini D, Majdic G, Tonon G, Trainor PA, Brendolan A.
IL-10 promotes homeostatic proliferation of human CD8(+) memory T cells and, when produced by CD1c(+) DCs, shapes naive CD8(+) T-cell priming.
Eur J Immunol. 2016 Jul;46(7):1622-32.
Nizzoli G, Larghi P, Paroni M, Crosti MC, Moro M, Neddermann P, Caprioli F, Pagani M, De Francesco R, Abrignani S, Geginat J.
c-Myc modulation & acetylation is a key HDAC inhibitor target in cancer.
Clin Cancer Res. 2016 Jun 29. pii: clincanres.2388.2015. [Epub ahead of print]
Angela N, Carafa V, Conte M, Tambaro FP, Abbondanza C, Martens JH, Nees M, Benedetti R, Pallavicini I, Minucci S, Garcia-Manero G, Iovino F, Lania G, Ingenito C, Belsito Petrizzi V, Stunnenberg HG, Altucci L.
A Myc-driven self-reinforcing regulatory network maintains mouse embryonic stem cell identity.
Nat Commun. 2016 Jun 15;7:11903. doi: 10.1038/ncomms11903.
Fagnocchi L, Cherubini A, Hatsuda H, Fasciani A, Mazzoleni S, Poli V, Berno V, Rossi RL, Reinbold R, Endele M, Schroeder T, Rocchigiani M, Szkarłat Ż, Oliviero S, Dalton S, Zippo A.
Identification of MYC-Dependent Transcriptional Programs in Oncogene-Addicted Liver Tumors.
Cancer Res. 2016 Jun 15;76(12):3463-72. doi: 10.1158/0008-5472.CAN-16-0316. Epub 2016 Apr 13.
Kress TR, Pellanda P, Pellegrinet L, Bianchi V, Nicoli P, Doni M, Recordati C, Bianchi S, Rotta L, Capra T, Ravà M, Verrecchia A, Radaelli E, Littlewood TD, Evan GI, Amati B.