HMGB1 is upregulated in the airways in asthma and potentiates airway smooth muscle contraction via TLR4.

J Allergy Clin Immunol. 2017 Feb 23. pii: S0091-6749(17)30047-7. doi: 10.1016/j.jaci.2016.11.049. [Epub ahead of print]
Di Candia L, Gomez E, Venereau E, Chachi L, Kaur D, Bianchi ME, Challiss RA, Brightling CE, Saunders RM.

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