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  1. Recent Publication
    Non-covalent and covalent modifications modulate the reactivity of monomeric mammalian globins.
    Biochim Biophys Acta. 2013 Feb 14.
    Multimeric globins (e.g., hemoglobin) are considered to be the prototypes of allosteric enzymes, whereas monomeric globins (e.g., myoglobin; Mb) usually are assumed to be non-allosteric. more…

  2. Recent Publication
    Sequence-Specific Transcription Factor NF-Y Displays Histone-like DNA Binding and H2B-like Ubiquitination.
    Cell. 2013 Jan 17;152(1-2):132-43.
    The sequence-specific transcription factor NF-Y binds the CCAAT box, one of the sequence elements most frequently found in eukaryotic promoters. NF-Y is composed of the NF-YA and NF-YB/NF-YC subunits, more…

  3. Recent Publication
    Identification of the molecular site of ivabradine binding to HCN4 channels.
    PLoS One. 2013;8(1):e53132.
    Ivabradine is a specific heart rate-reducing agent approved as a treatment of chronic stable angina. Its mode of action involves a selective and specific block of HCN channels, more…

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