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  1. Recent Publication

    Recent Publication
    HMGB1 and leukocyte migration during trauma and sterile inflammation.
    Mol Immunol. 2012 Dec 1. pii: S0161-5890(12)00451-8
    Abstract
    HMGB1 is a nuclear protein that is released or secreted following trauma or severe cellular stress. Extracellular HMGB1 triggers inflammation and recruits leukocytes to the site of tissue damage. more…

    February 24, 2013
  2. Recent Publication

    Recent Publication
    Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release.
    J Exp Med. 2012 Aug 27;209(9):1519-28.
    Abstract
    Tissue damage causes inflammation, by recruiting leukocytes and activating them to release proinflammatory mediators. We show that high-mobility group box 1 protein (HMGB1) orchestrates… more…

    February 24, 2013

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